Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast

Yansong Miao; Xuemei Han; Liangzhen Zheng; Ying Xie; Yuguang Mu; John R. Yates; David G. Drubin

doi:10.1038/ncomms11265

Nature Communications (Apr 2016)

Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast

Yansong Miao,
Xuemei Han,
Liangzhen Zheng,
Ying Xie,
Yuguang Mu,
John R. Yates,
David G. Drubin

Affiliations

Yansong Miao: Department of Molecular and Cell Biology, University of California
Xuemei Han: Department of Chemical Physiology, The Scripps Research Institute
Liangzhen Zheng: School of Biological Sciences, Nanyang Technological University
Ying Xie: School of Chemical and Biomedical Engineering, Nanyang Technological University
Yuguang Mu: School of Biological Sciences, Nanyang Technological University
John R. Yates: Department of Chemical Physiology, The Scripps Research Institute
David G. Drubin: Department of Molecular and Cell Biology, University of California

DOI: https://doi.org/10.1038/ncomms11265
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 12

Abstract

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Metaphase cells preferentially promote actin cable assembly through cyclin-dependent kinase 1 (Cdk1) activity. Here the authors identify fimbrin as one of the main metaphase Cdk1 targets for cell cycle regulation of actin cable assembly in budding yeast.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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