Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa

Rubini Kannangara; Lina Siukstaite; Jonas Borch-Jensen; Bjørn Madsen; Kenneth T. Kongstad; Dan Staerk; Mads Bennedsen; Finn T. Okkels; Silas A. Rasmussen; Thomas O. Larsen; Rasmus J. N. Frandsen; Birger Lindberg Møller

doi:10.1038/s41467-017-02031-z

Nature Communications (Dec 2017)

Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa

Rubini Kannangara,
Lina Siukstaite,
Jonas Borch-Jensen,
Bjørn Madsen,
Kenneth T. Kongstad,
Dan Staerk,
Mads Bennedsen,
Finn T. Okkels,
Silas A. Rasmussen,
Thomas O. Larsen,
Rasmus J. N. Frandsen,
Birger Lindberg Møller

Affiliations

Rubini Kannangara: Plant Biochemistry Laboratory, Department of Plant and Environmental Sciences, University of Copenhagen
Lina Siukstaite: Plant Biochemistry Laboratory, Department of Plant and Environmental Sciences, University of Copenhagen
Jonas Borch-Jensen: VILLUM Center For Bioanalytical Sciences, Department of Biochemistry and Molecular Biology, University of Southern Denmark
Bjørn Madsen: Chr. Hansen A/S, Bøge Alle 10-12
Kenneth T. Kongstad: Department of Drug Design and Pharmacology, University of Copenhagen
Dan Staerk: Department of Drug Design and Pharmacology, University of Copenhagen
Mads Bennedsen: Chr. Hansen A/S, Bøge Alle 10-12
Finn T. Okkels: Chr. Hansen A/S, Bøge Alle 10-12
Silas A. Rasmussen: Department of Biotechnology and Biomedicine, The Technical University of Denmark
Thomas O. Larsen: Department of Biotechnology and Biomedicine, The Technical University of Denmark
Rasmus J. N. Frandsen: Department of Biotechnology and Biomedicine, The Technical University of Denmark
Birger Lindberg Møller: Plant Biochemistry Laboratory, Department of Plant and Environmental Sciences, University of Copenhagen

DOI: https://doi.org/10.1038/s41467-017-02031-z
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 12

Abstract

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Carminic acid is a widely applied red colorant that is still harvested from insects because its biosynthesis is not fully understood. Here, the authors identify and characterize a membrane-bound C-glucosyltransferase catalyzing the final step during carminic acid biosynthesis.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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