Hip fracture and cancer: descriptive epidemiological study demonstrating a paradigm shift in common orthopedic trauma

Juri Teramoto; Yasuhiro Homma; Taiji Watari; Koju Hayashi; Tomonori Baba; Nobuhiko Hasegawa; Daisuke Kubota; Tatsuya Takagi; Muneaki Ishijima

Journal of Joint Surgery and Research (Mar 2025)

Hip fracture and cancer: descriptive epidemiological study demonstrating a paradigm shift in common orthopedic trauma

Juri Teramoto,
Yasuhiro Homma,
Taiji Watari,
Koju Hayashi,
Tomonori Baba,
Nobuhiko Hasegawa,
Daisuke Kubota,
Tatsuya Takagi,
Muneaki Ishijima

Affiliations

Juri Teramoto: Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Yasuhiro Homma: Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Community Medicine and Research for Bone and Joint Diseases, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Corresponding author. Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Taiji Watari: Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Koju Hayashi: Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Tomonori Baba: Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Pathophysiology for Locomotive Diseases, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Nobuhiko Hasegawa: Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Daisuke Kubota: Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Tatsuya Takagi: Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Muneaki Ishijima: Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Community Medicine and Research for Bone and Joint Diseases, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Pathophysiology for Locomotive Diseases, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Journal volume & issue: Vol. 3, no. 1
pp. 17 – 20

Abstract

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Purpose: Despite the increase both in patients with cancer and those with proximal femoral fractures (PFFs), details of the characteristics of non-pathological PFFs in patients undergoing cancer treatment are unknown. The purpose of this retrospective study was to investigate the characteristics and issues of patients with active cancer who have non-pathological PFFs. Methods: This was a retrospective, observational, descriptive epidemiological study. A total of 376 patients were admitted to Juntendo University hospital with a diagnosis of PFF. Six of these patients had metastasis-related pathological fractures and were excluded from this study. The remaining 370 patients comprised 100 men and 270 women. Results: The mean patient age was 78.6 ± 11.2 years. Fractures included 141 trochanteric femoral fractures and 229 femoral neck fractures. Of these, 39 (10.5%) of the patients had active cancer, 55 (14.9%) has a history of past cancer, and 276 (74.6%) had no cancer. Among the 39 patients with active cancer, 13 (33.3%) received glucocorticoids; furthermore, 10 (76.9%) of these 13 patients were not receiving medications to prevent osteoporosis. Lastly, 9 of the 39 falls were hospitalization-related, but 6 (66.7%) of these 9 patients did not undergo rehabilitation during hospitalization. Conclusions: Approximately one in ten patients with PFF in this study were undergoing cancer treatment. Moreover, one in four patients with PFF were cancer-related. Therefore, orthopedic surgeons should have basic knowledge about cancer management in hip fracture.

Published in Journal of Joint Surgery and Research

ISSN: 2949-7051 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Surgery
Website: https://www.sciencedirect.com/journal/journal-of-joint-surgery-and-research

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