Relationship Between Serum CA125 Level with Malnutrition and Functional Parameters in Peritoneal Dialysis Patients

Abstract

Introduction: Peritoneal dialysis is one of the most efficient treatment in ESRD. Peritoneal sclerosis and malnutrition are side effects of peritoneal dialysis. Cancer antigen 125(CA125) is made by peritoneal mesothelial cells and increases during peritoneal inflammation. Peritoneal biopsy s an invasive method using for diagnosis of peritoneal sclerosis but serum CA125 is a noninvasive method used for prediction of peritoneal dialysis recently. The aim of this study was to investigate the relationship between serum CA125 with peritoneal function and malnutrition parameters. Materials and Methods:  This cross- sectional study was carried out in Yazd 2014. A total of 50 peritoneal dialysis patients were selected by convenience sampling. A questionnaire consists of malnutrition and peritoneal functional parameters and demographic characteristics of patents was completed. SPSS version 20 and T test. Anova, chi -square and logistic regression tests used for data analysis. Results: In this study, there was a direct association between serum CA125 and serum triglyceride, LDL and invers more association between CA125 and serum albumin but there was no association between CA125 and peritoneal function parameters.

Keywords

• Peritoneal function
• Malnutrition factors
• Peritoneal dialysis
• CA125