Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq

Uri Weissbein; Maya Schachter; Dieter Egli; Nissim Benvenisty

doi:10.1038/ncomms12144

Nature Communications (Jul 2016)

Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq

Uri Weissbein,
Maya Schachter,
Dieter Egli,
Nissim Benvenisty

Affiliations

Uri Weissbein: Department of Genetics, The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University
Maya Schachter: Department of Genetics, The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University
Dieter Egli: The New York Stem Cell Foundation Research Institute
Nissim Benvenisty: Department of Genetics, The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University

DOI: https://doi.org/10.1038/ncomms12144
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 8

Abstract

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Chromosomal aberrations can be detected by global gene expression analysis. Here, the authors report eSNP-Karyotyping, a new method that can detect chromosomal aberrations by measuring the ratio of expression between the two alleles without comparison to a matched diploid sample.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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