Vancomycin-resistant Enterococcus faecium bacteremia in End-Stage Renal Disease (ESRD) and Focal Segmental Glomerulosclerosis (FSGS) patient under hemodialysis

Abstract

Background: Today, one of the important challenges related to the emergence of antibiotic resistance among hospital-acquired infections is Vancomycin-Resistant Enterococci (VRE). The identification of the hospital transfer pattern and accurate laboratory diagnosis can be effective in preventing or selecting the appropriate antibiotics for the treatment of these types of infections, especially in hemodialysis patients. Case report: This report discusses the hospitalization of a 2.5-year-old boy with End-Stage Renal Disease (ESRD) and Focal Segmental Glomerulosclerosis (FSGS) at a nephrology center in a tertiary hospital. The patient received hemodialysis treatment, followed by an abdominal tap, which revealed an infection. Peritoneal and blood cultures were conducted using the BACT/ALERT®3D instrument, and the results indicated a bacterial infection during the hospital stay. Further analysis confirmed that the infection was caused by enterococci, and susceptibility testing revealed that the isolated strain was resistant to vancomycin. Fortunately, the enterococci infection responded well to linezolid antibiotic treatment, administered at a dose of 600 mg PO/IV q12hr for 14 days. Conclusions: This report highlights the importance of healthcare workers being aware of the transmission routes of VRE among patients. It emphasizes the need for appropriate hand hygiene, sterility of extracorporeal devices, and proper catheter care in medical centers.

Keywords

• Enterococcus faecium
• Vancomycin-resistant
• Bacteremia
• Hospital infection
• Case report