Вестник трансплантологии и искусственных органов (Sep 2023)

Development of graft-versus-host disease in a liver recipient. Clinical observations and literature review

  • S. E. Voskanyan,
  • V. L. Korobka,
  • V. E. Syutkin,
  • A. R. Monakhov,
  • A. P. Maltseva,
  • E. S. Pak,
  • R. V. Korobka,
  • E. I. Kolodyazhny,
  • S. I. Zubenko,
  • Yu. V. Voskanyan,
  • V. Yu. Kotsiyaev

DOI
https://doi.org/10.15825/1995-1191-2023-3-38-49
Journal volume & issue
Vol. 25, no. 3
pp. 38 – 49

Abstract

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Graft-versus-host disease (GvHD) after liver transplantation (LT) occurs in 0.2–0.3% of liver transplant recipients. Each case is characterized by individual peculiarities of the clinical picture. There are no standards or clinical guidelines for the treatment of GvHD in solid organ recipients; mortality remains very high among these patients. We present two clinical cases of verified GvHD that developed early after LT, and we offer a brief review of the current state of the art in the study of this problem.

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