Delta Journal of Ophthalmology (Jan 2023)

Posterior capsule opacification following implantation of hydrophilic compared to hydrophobic intraocular lenses

  • Karim R.A.E Rehan,
  • Sheriff Elwan,
  • Ossama T.S Nada,
  • Rania S Elkitkat

DOI
https://doi.org/10.4103/djo.djo_63_22
Journal volume & issue
Vol. 24, no. 2
pp. 100 – 104

Abstract

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Purpose The aim of this study was to compare the onset of posterior capsule opacification (PCO) in patients who underwent hydrophilic intraocular lens (IOLs) implantation compared with hydrophobic IOL implantation. Patients and methods This is a retrospective, comparative, observational study that was conducted on patients who sought medical advice at the Ophthalmology Outpatient Clinic of the Ophthalmology Department, Ain Shams University, Cairo, Egypt, and underwent uneventful phacoemulsification cataract surgery and hydrophilic or hydrophobic acrylic nonheparinized IOL implantation. The electronic medical records were searched for surgeries performed by equal-caliber experienced surgeons. All enrolled cases underwent ‘in-the-bag’ implantation of a square-edged IOL after continuous curvilinear capsulorhexis with cortical cleanup. The evaluated data included age, sex, medical history, date of phacoemulsification cataract surgery, type of implanted IOL, and the duration till Nd : YAG capsulotomy was needed. The patients were divided into two groups: group 1 (29 eyes of 29 patients), which underwent hydrophilic acrylic IOL implantation, and group 2 (27 eyes of 27 patients), which underwent hydrophobic acrylic IOL implantation. Results There was no statistically significant difference between the hydrophilic and hydrophobic IOLs regarding the time of onset of postoperative PCO development [median=1.92 years, interquartile range=1.17–2.75 in group 1 and 1.34 years (0.5–2.41) in group 2, P=0.192). In addition, there was no statistically significant relation between the onset of PCO and the general medical condition of the enrolled patients, including diabetes mellitus, hypertension, hepatitis C virus, renal disease, systemic lupus erythematosus, hypocalcemia, and patients on chemotherapy (P>0.05). Conclusion There was no statistically significant difference in the onset of PCO development with different IOL materials. Moreover, the patients’ general medical condition did not show a significant association with PCO incidence.

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