Application of a borate-containing glass for the treatment of trophic wounds in children, suffering myelodysplasia

Abstract

Objective. To estimate the possibility of application of a borate-containing glass material while treating trophic wounds in children, suffering myelodysplasia. Маterials and methods. The data, concerning 3 children, who, while their newborn time were operated on for a spinal cord hernias, are presented. All the children have had myelodysplastic disordered trophic wound of the lower extremities, causing severe course of the wounds or the bedsores healing. Bioactive borate-containing glass «Mirragen», manufactured in USA, was proposed by medical centre «Меdyvo» for treatment of trophic wounds in children. Results. Application of bioactive borate-containing glass while treating trophic wounds in children, suffering myelodysplasia, was effective. Deep wounds during 8 weeks have had healed completely without complications, and a superficial wound—bedsore - during 5 weeks. The wounds have epithelized steadily, starting together from the bottom and periphery with velocity up to 12-15% of their square weekly. Negative general or local reaction towards a borate-containing glass in the patients was absent. Conclusion. Тemporary biomaterial, structured by a carcass, made of a borate-containing glass, guarantees a necessary form establishment, needed for creation of a new tissues and promotion of rapid healing of the wounds. Application of a bioactive borate-containing glass constitutes a safe and efficient method of treatment for trophic wounds in children, suffering myelodysplasia.

Keywords

• bioactive borate-containing glass; poorly healing wounds; children