Archives of Biological Sciences (Jan 2002)

Effects of acute hypoxia on the energy status and antioxidant defense system in the blood of carp - Cyprinvs carpio L.

  • Žikić Radoslav V.,
  • Štajn Andraš Š.,
  • Pavlović Slađan Z.,
  • Ognjanović Branka I.,
  • Maletić Snežana D.,
  • Marković Mirjana D.,
  • Dragićević-Đoković Ljiljana M.,
  • Radojičić Ratko M.,
  • Saičić Zorica S.

DOI
https://doi.org/10.2298/ABS0202011Z
Journal volume & issue
Vol. 54, no. 1-2
pp. 11 – 18

Abstract

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The influence of acute hypoxia on glucose, pyruvate, lipid peroxide (LP) reduced glutathione (GSH) concentrations and lactate level in the whole blood of carp (Cyprinus carpio L) under aquarium conditions were studied. The activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), the concentrations of ATP and ADP and ATP/ADP ratio in the red blood cells (RBCs) were analyzed. Glutathione-S-transferase (GST) activity was determined in the plasma. Our experiments showed that short-term and long-term hypoxia causes significant changes of all examined haema-tological parameters. Increased concentration of LP and increased SOD CAT and GST activities, as well as a decreased GSH-Px activity showed that under hypoxic conditions oxidative stress and RBCs damage were produced.