Retinoblastoma in patients with regressed retinopathy of prematurity

Abstract

Retinopathy of prematurity (ROP) is a well-known clinical entity in premature babies. We report two patients (1 and 2) with regressed ROP who later presented with retinoblastoma (RB). To the best of our knowledge, there is only one such report in the literature so far. Two unrelated patients 1 and 2, born at 32 weeks gestation were screened for ROP at 34 weeks gestation. This showed Zone II Stage II ROP which regressed by 38 weeks of gestation on follow-up. Both patients were lost to follow-up by 40 weeks of gestation. They presented at four years of age with white reflex in the eye. Patient 1 was found to have unilateral and patient 2 bilateral RB. The occurrence of RB in these patients with regressed ROP is probably coincidental.

Keywords

• Myopia
• prethreshold retinopathy of prematurity
• retinopathy of prematurity
• Retinopathy of prematurity
• screening
• survey
• Anthrax
• community-acquired methicillin-resistant Staphyloccus aureus
• orbital cellulitis
• preseptal cellulitis
• Intrastromal corneal ring segments; keraring; post-LASIK ectasia
• Blebitis
• bleb leak
• microbiology
• ocular surface diseases
• risk factors
• Early glaucoma
• retinal nerve fiber layer thickness
• spectral optical coherence tomography / scanning laser ophthalmoscope
• Blowout
• diplopia
• prism
• strabismus
• Ocular trauma
• open globe injury
• preoperative visual acuity
• prognostic factors
• relative afferent pupillary defect
• Anterior chamber depth
• axial length
• lens thickness
• phacomorphic glaucoma
• risk factor
• Refractive errors
• Schoolgirls
• visual impairments
• Cataract
• intraocular lens
• monovision
• presbyopia
• pseudophakic
• Accommodative esotropia
• atropine
• cycloplegia
• esotropia
• Optic disc cupping
• optic disc pallor
• suprasellar tumor
• glaucoma
• neuroimaging
• Dislocated nucleus
• intraocular lens
• iris claw lens
• pars plana vitrectomy
• Retinoblastoma
• retinopathy of prematurity
• risk factor