Trials (Jul 2024)

An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus an aminoglycoside + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial—an update to the published protocol

  • Rindra Vatosoa Randremanana,
  • Mihaja Raberahona,
  • Mamy Jean de Dieu Randria,
  • Josephine Bourner,
  • Gabriella Zadonirina,
  • Hanitra Razananaivo,
  • Théodora Mayouya-Gamana,
  • Reziky Mangahasimbola,
  • Elise Pesonel,
  • Annelies Gillesen,
  • Minoarisoa Rajerison,
  • Voahangy Andrianaivoarimanana,
  • Tansy Edwards,
  • Peter Horby,
  • Piero Olliaro

DOI
https://doi.org/10.1186/s13063-024-08302-7
Journal volume & issue
Vol. 25, no. 1
pp. 1 – 3

Abstract

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Abstract This article reports an update to the protocol of the IMASOY trial, which was prospectively registered on clinicaltrials.gov (NCT04110340) in October 2019.