Possible adverse effects of immunotherapy in non-small cell lung cancer; treatment and follow-up of three cases

Paul Zarogoulidis; Panos Chinelis; Anastasia Athanasiadou; Theodora Tsiouda; Georgia Trakada; Anastasios Kallianos; Lemonia Veletza; Dimitris Hatzibougias; Electra Mihalopoulou; Eirini Goupou; Christoforos Kosmidis; Chrysanthi Sardeli; Haidong Huang; Wolfgang Hohenforst-Schmidt

doi:10.1016/j.rmcr.2017.07.004

Respiratory Medicine Case Reports (Jan 2017)

Possible adverse effects of immunotherapy in non-small cell lung cancer; treatment and follow-up of three cases

Paul Zarogoulidis,
Panos Chinelis,
Anastasia Athanasiadou,
Theodora Tsiouda,
Georgia Trakada,
Anastasios Kallianos,
Lemonia Veletza,
Dimitris Hatzibougias,
Electra Mihalopoulou,
Eirini Goupou,
Christoforos Kosmidis,
Chrysanthi Sardeli,
Haidong Huang,
Wolfgang Hohenforst-Schmidt

Affiliations

Paul Zarogoulidis: Pulmonary Department-Oncology Unit, “Theageneio” Anticancer Hospital, Thessaloniki, Greece
Panos Chinelis: Pulmonary Oncology Unit, “G. Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
Anastasia Athanasiadou: Pulmonary Oncology Unit, “G. Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
Theodora Tsiouda: Pulmonary Oncology Unit, “G. Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
Georgia Trakada: Division of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra Hospital, Athens, Greece
Anastasios Kallianos: Division of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra Hospital, Athens, Greece
Lemonia Veletza: Division of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra Hospital, Athens, Greece
Dimitris Hatzibougias: Microdiagnostics, Pathology Private Center, Thessaloniki, Greece
Electra Mihalopoulou: Microdiagnostics, Pathology Private Center, Thessaloniki, Greece
Eirini Goupou: Microdiagnostics, Pathology Private Center, Thessaloniki, Greece
Christoforos Kosmidis: Surgery Department, “Interbalkan” European Medical Center, Thessaloniki, Greece
Chrysanthi Sardeli: Pharmacology-Clinical Pharmacology, Department of Clinical, Pharmacology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece
Haidong Huang: Department of Respiratory and Critical Care Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
Wolfgang Hohenforst-Schmidt: Sana Clinic Group Franken, Department of Cardiology / Pulmonology / Intensive Care / Nephrology, “Hof” Clinics, University of Erlangen, Hof, Germany

DOI: https://doi.org/10.1016/j.rmcr.2017.07.004
Journal volume & issue: Vol. 22, no. C
pp. 101 – 105

Abstract

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In the past decade novel agents are on the market for non-small cell lung cancer adenocarcinoma based on pharmacogenomics. The epidermal growth factor receptor mutation, anaplastic lymphoma kinase and programmed death-ligand 1 investigation is necessary in the everyday clinical practice for the oncologic patient. Immunotherapy is nowadays the novel therapy for advanced stage non-small cell lung cancer with two agents nivolumab and pembrolizumab. In the current case series we will present adverse effects from our centers and comment on the treatment and follow-up of the patients.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: http://www.journals.elsevier.com/respiratory-medicine-case-reports/

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