High Levels of Antibiotic Resistance in MDR-Strong Biofilm-Forming <i>Salmonella</i> Typhimurium ST34 in Southern China

Abstract

Salmonella enterica subsp. enterica serovar Typhimurium (S. typhimurium) is an important zoonotic pathogen with important public health significance. To understand S. typhimurium’s epidemiological characteristics in China, multi-locus sequence typing, biofilm-forming ability, antimicrobial susceptibility testing, and resistant genes of isolates from different regions and sources (human, food) were investigated. Among them, ST34 accounted for 82.4% (243/295), with ST19 ranking second (15.9%; 47/295). ST34 exhibited higher resistance levels than ST19 (p p p p S. typhimurium ST34 with strong biofilm-forming ability, posing concerns for public health safety.

Keywords

• <i>S. typhimurium</i>
• ST34
• drug resistance
• ACSSuT
• biofilm