Pharmaceutics (Feb 2022)

Recent Developments in Metallic Nanomaterials for Cancer Therapy, Diagnosing and Imaging Applications

  • Dan Nicolae Păduraru,
  • Daniel Ion,
  • Adelina-Gabriela Niculescu,
  • Florentina Mușat,
  • Octavian Andronic,
  • Alexandru Mihai Grumezescu,
  • Alexandra Bolocan

DOI
https://doi.org/10.3390/pharmaceutics14020435
Journal volume & issue
Vol. 14, no. 2
p. 435

Abstract

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Cancer continues to represent a global health concern, imposing an ongoing need to research for better treatment alternatives. In this context, nanomedicine seems to be the solution to existing problems, bringing unprecedented results in various biomedical applications, including cancer therapy, diagnosing, and imaging. As numerous studies have uncovered the advantageous properties of various nanoscale metals, this review aims to present metal-based nanoparticles that are most frequently employed for cancer applications. This paper follows the description of relevant nanoparticles made of metals, metal derivatives, hybrids, and alloys, further discussing in more detail their potential applications in cancer management, ranging from the delivery of chemotherapeutics, vaccines, and genes to ablative hyperthermia therapies and theranostic platforms.

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