Jichu yixue yu linchuang (Oct 2023)
Research progress of sodium-glucose cotransporter 2 inhibitor in non-alcoholic fatty liver disease
Abstract
Sodium-glucose cotransporter 2 inhibitor (SGLT-2i) is a new type of anti-diabetes drug. Clinical studies have shown that SGLT-2i plays a beneficial role in the treatment of patients with non-alcoholic fatty liver disease (NAFLD). SGLT-2i can reduce hepatic endoplasmic reticulum stress, regulate inflammatory reaction, improve liver fibrosis and increase hepatocyte autophagy to alleviate symptoms of NAFLD patients.
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