Química Nova (Jan 2007)

Uma visão da química bioinorgânica medicinal Medicinal bioinorganic chemistry

  • Anna Maria Canavarro Benite,
  • Sérgio de Paula Machado,
  • Eliezer J. Barreiro

DOI
https://doi.org/10.1590/S0100-40422007000800045
Journal volume & issue
Vol. 30, no. 8
pp. 2062 – 2067

Abstract

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Metals play a vital role in human and plant physiology and important research is directed towards exploring the interrelated mechanisms that govern their interactions with biomolecules. Bioinorganic medicinal chemistry studies the functions, processing, storage and applications of metal ions and their complexes in biological systems. This paper presents a brief discussion about on interactions of metals with biomolecules that determine their intracellular accumulation, where metal ions may fulfill essential functions in cellular metabolism or, in certain cases, exert toxic effects towards cells.

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