Nature Communications (Sep 2021)

Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques

  • Romain Marlin,
  • Veronique Godot,
  • Sylvain Cardinaud,
  • Mathilde Galhaut,
  • Severin Coleon,
  • Sandra Zurawski,
  • Nathalie Dereuddre-Bosquet,
  • Mariangela Cavarelli,
  • Anne-Sophie Gallouët,
  • Pauline Maisonnasse,
  • Léa Dupaty,
  • Craig Fenwick,
  • Thibaut Naninck,
  • Julien Lemaitre,
  • Mario Gomez-Pacheco,
  • Nidhal Kahlaoui,
  • Vanessa Contreras,
  • Francis Relouzat,
  • Raphaël Ho Tsong Fang,
  • Zhiqing Wang,
  • Jerome Ellis,
  • Catherine Chapon,
  • Mireille Centlivre,
  • Aurelie Wiedemann,
  • Christine Lacabaratz,
  • Mathieu Surenaud,
  • Inga Szurgot,
  • Peter Liljeström,
  • Delphine Planas,
  • Timothée Bruel,
  • Olivier Schwartz,
  • Sylvie van der Werf,
  • Giuseppe Pantaleo,
  • Mélanie Prague,
  • Rodolphe Thiébaut,
  • Gerard Zurawski,
  • Yves Lévy,
  • Roger Le Grand

DOI
https://doi.org/10.1038/s41467-021-25382-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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In this study, Marlin et al. provide insights into the potential use of subunit vaccines that induce a high level of protection against SARS-CoV-2 in animal models.