Cardiac resyncronization therapy with or without cardioverter-defibrillator versus defibrillator therapy alone, Pereira (Colombia): a cohort study

Abstract

Objective: To evaluate survival in patients with cardiac resynchronization with or without cardioverterdefibrillator versus patients with implantable cardioverter-defibrillator alone Materials and methods: Retrospective cohort, the primary end point was death from cardiac causes, the exposure was electrophysiological therapies, and the information sources were medical files and other records. Results: 70 elderly patients with functional devices; 82 % of them received optimized medical therapy. No significant association was found between survival of patients with cardiac resynchronization therapy with or without defibrillator and cardioverter-defibrillator therapy alone (log rank test, p = 0.54), but the former had a longer survival time (ANOVA p = 0.0012). The hazard ratio was 0.017 for day 371 and 0.15 for day 2169. Fourteen deaths occurred during the observation period, three of them from non-cardiac causes. Conclusion: Cardiac resynchronization therapy was associated with significantly longer survival time.

Keywords

• Cardiac Resynchronization Therapy
• Colombia
• Defibrillators
• Implantable
• Survival Analysis