Кубанский научный медицинский вестник (Oct 2014)

Prediction for vascular mild cognitive impairment using the p300 event-related potentials technique

  • Yu. V. Sturova,
  • N. R. Plotnikova,
  • G. A. Kostomarova,
  • E. R. Barantsevich,
  • O. V. Posokhina,
  • E. V. Verbitskaya

Journal volume & issue
no. 5
pp. 117 – 122

Abstract

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Evoked potentials technique owing to informativeness and diagnostic value is widely used in clinical and experimental studies. Herein, we investigated whether the auditory P300 event-related potentials predict syndrome vascular mild cognitive impairment. 42 patients with I and II stages of discirulatory encephalopathy (50-70 years) included in clinical study. The discriminant analysis method was used to work out an equation with two variables as predictors - the P300 latent period and patient's age. The diagnostic accuracy of the discriminant equation at a cut-off -0,268 was established through receiver operating characteristic (ROC) analysis (sensitivity 80%, specificity 74,1%).

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