Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology (May 2024)

Gallic Acid: Derivatives and Biosynthesis, Pharmacological and Therapeutic Effect, Biological Activity

  • Ali Erdem ŞABİK,
  • Mustafa SEVİNDİK,
  • Falah Saleh MOHAMMED,
  • Imran UYSAL,
  • Celal BAL

DOI
https://doi.org/10.15835/buasvmcn-fst:2023.0017
Journal volume & issue
Vol. 81, no. 1

Abstract

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Phenolic compounds are important compounds responsible for many therapeutic, pharmacological, and biological activities. They are compounds that do not have nutritional properties but are very important from a medical point of view. In this review, general properties, derivatives and biosynthesis, pharmacological and therapeutic effects, biological activities, and toxic and side effects of gallic acid were reviewed. As a result of the literature research, it has been seen that it has pharmacological and therapeutic effects such as gastrointestinal diseases, cardiovascular disease, neuropsychological and neuroprotective conditions, metabolic diseases, allergic skin, antianxiety, wound healing activity, rheumatoid arthritis, colitis, obesity. It has also been reported to have biological activities such as antioxidant, anti-melanogenic, antimicrobial, anti-ageing, antidiabetic, antiapoptotic, anticancer, anti-inflammatory, hepatoprotective, antiviral, cytotoxic, antidepressant. In this context, it has been determined that gallic acid is an important phenolic compound.

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