The use of plant extracts in dermatocosmetic preparations, instead of chemical synthesis products, is a trend that is becoming more prominent in an effort to meet customer needs and guarantee product quality. In this context, the aim of the work is to present the obtaining and characterization of the extract of Acmella oleracea, by classical or combined liquid-solid extraction methods. Their physical-chemical characterization was based on the determination of the content of polyphenols and flavonoids and their antioxidant activity. The emulsion based on Acmella oleracea extract was preliminarily characterized in terms of stability and homogeneity.