Italian Journal of Food Safety (Dec 2008)

ALTERATION OF GENE EXPRESSION IN LEUKOCYTES FROM RECOMBINANT SOMATOTROPIN TREATED ANIMALS: SEARCHING FOR INSPECTION INDICATORS

  • NR Brizioli,
  • D. Gianfaldoni,
  • A. Guidi,
  • M. Mazzi,
  • R. Rosati,
  • L Castigliego,
  • A. Armani,
  • G Grifoni

DOI
https://doi.org/10.4081/ijfs.2008.2.29
Journal volume & issue
Vol. 1, no. 2
pp. 29 – 31

Abstract

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Besides immunochemical approaches, biomolecular studies can be carried out in order to discover a greater number of biological indicators to be exploited for the identification of bovines treated with recombinant somatotropin (rbST). With this aim, we analysed the expression of a number of genes related to the somatotropic axis in leucocytes from rbST treated cows and non-treated animals. Significant differences were observed in the genes IGF-1,IGFBP-1, IGFBP-4 and the I- 5’UTR variant of the GHR gene.

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