Predictive value of neutrophil-to-lymphocyte ratio in in-hospital mortality in sepsis patients: A cross-sectional study

Abstract

Objective: To explore the predictive value of neutrophil-to-lymphocyte ratio (NLR) in in-hospital mortality in sepsis patients. Methods: A prospective observational cross-sectional study was conducted on 100 patients with septicemia. The data about the patient’s demography, medical history, general examination including pulse rate, blood pressure, etc, use of vasopressor support, need for renal replacement therapy, mechanical ventilation, outcome, and lab parameters including total lymphocyte count with neutrophil-to-lymphocyte ratio were recorded. And parameters between survivals and non-survivals were compared. Results: Out of 100 patients, 80% were from rural backgrounds. Most patients were 50 to 59 years old. 26 Patients were dead. The patients in the nonsurvivor group were older and more had a history of diabetes mellitus when compared with the survivor group. The non-survivor group had a higher NLR, APACHE II, and SOFA score. Conclusions: NLR is a readily available parameter and can be used as a good prognostic indicator for mortality in sepsis patients.

Keywords

• neutrophil-to-lymphocyte ratio
• sepsis
• intensive care unit
• mortality
• apache score
• sofa score