Use of sodium polystyrene sulfonate in an acute-on-chronic lithium poisoned patient: A case report

Abstract

A 35-year-old woman with an acute-on-chronic lithium overdose received multiple oral doses of sodium polystyrene sulfonate totaling 120 g over a 24-h period. During the 72 h after the institution of therapy, the serum lithium level decreased from 3.80 to 0.42 mEq/L. Multiple doses of sodium polystyrene sulfonate may be useful in lowering the serum lithium level in severely ill patients with acute renal failure, and can substitute hemodialysis.

Keywords

• Sodium polystyrene sulfonate
• Serum lithium level
• Lithium overdose
• Intensive care