Regulating Effect of Ginseng in Combination with Dandelion Root on Shanghuo Symptoms in Rats

Abstract

In order to improve the symptoms of "Shanghuo" and the universality of ginseng, the animals randomly divided into control group, the 2 and 4 g/kg ginseng group and ginseng dandelion root compatibility group were given intragastric administration for 19 days, respectively. Body temperature, blood pressure and 5-hydroxytryptamine (5-HT), thyroid-stimulating hormone (TSH), corticosterone (CORT) and other indicators associated with "Shanghuo" were measured. The results showed that the body temperature and blood pressure of the 2 and 4 g/kg groups were lower than those of the ginseng group, and the effect of the 4 g/kg group was more significant (P<0.05). Compared with the control group, the content of 5-HT in ginseng group decreased, and the contents of TSH, 17-hydroxy corticosteroid (17-OHCS), CORT, tumor necrosis factor-α (TNF-α) were significantly increased (P<0.05). Compared with ginseng group, the contents of 5-HT in the combination group of 2 and 4 g/kg ginseng and dandelion root compatibility group were increased, and the contents of TSH, 17-OHCS, CORT, TNF-α were significantly decreased (P<0.05). The results indicated that compatibility of ginseng and dandelion root could improve the value of ginseng and dandelion root, and regulate the symptoms of "Shanghuo" caused by ginseng consumption.

Keywords

• ginseng
• dandelion root
• compatibility
• "shanghuo"
• blood pressure