An in vitro study shows the potential of Nostoc commune (Cyanobacteria) polysaccharides extract for wound-healing and anti-allergic use in the cosmetics industry

Chung-Chih Tseng:; Han-Yang Yeh; Zhen-Hao Liao; Sheng-Wen Hung; Boryuan Chen; Po-Tsang Lee; Fan-Hua Nan; Wen-Ling Shih; Chia-Ching Chang; Meng-Chou Lee

Journal of Functional Foods (Dec 2021)

An in vitro study shows the potential of Nostoc commune (Cyanobacteria) polysaccharides extract for wound-healing and anti-allergic use in the cosmetics industry

Chung-Chih Tseng:,
Han-Yang Yeh,
Zhen-Hao Liao,
Sheng-Wen Hung,
Boryuan Chen,
Po-Tsang Lee,
Fan-Hua Nan,
Wen-Ling Shih,
Chia-Ching Chang,
Meng-Chou Lee

Affiliations

Chung-Chih Tseng:: Department of Dentisry, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung City 81342, Taiwan; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung City 80424, Taiwan
Han-Yang Yeh: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan
Zhen-Hao Liao: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan
Sheng-Wen Hung: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan
Boryuan Chen: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan
Po-Tsang Lee: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan
Fan-Hua Nan: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan
Wen-Ling Shih: Department of Biological Science and Technology, National Pingtung University of Science and Technology, Pingtung 912, Taiwan
Chia-Ching Chang: Department of Dentisry, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung City 81342, Taiwan; Corresponding authors at: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan (M.C. Lee). Department of Dentisry, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung City 81342, Taiwan (C.C. Chang).
Meng-Chou Lee: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan; Center of Excellence for Ocean Engineering, National Taiwan Ocean University, Keelung City 20224, Taiwan; Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung City 20224, Taiwan; Corresponding authors at: Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan (M.C. Lee). Department of Dentisry, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung City 81342, Taiwan (C.C. Chang).

Journal volume & issue: Vol. 87
p. 104754

Abstract

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Nostoc commune has abundant bioactive compounds, which are valuable in medical, cosmeceutical, and nutraceutical fields. Currently, the demand for native bioactive compounds in the cosmetic industry is greater than ever, especially with regard to algae extracts. In this study, we evaluated the biochemical compounds, safety, and effect on wound-healing and anti-allergic properties of Nostoc commune polysaccharide-rich extract (NCPE) in an in vitro study. The results showed that an extract with 221.69 ± 25.56 mg g−1 polysaccharide mainly consists of glucose (73.2%) with abundant bioactive compounds (total phenolic, total flavonoids, and sulfates) and some elements (K, Sr, Mn, Ba, and Ni). Cytotoxicity and heavy metal assays revealed that the extract was safe and available. Cell culture experiments showed that the polysaccharide effectively inhibits IL-6, and β-hexosaminidase, but promotes collagen I secretion. These findings suggest that the extract may be a useful resource in the development of wound-healing and anti-allergic cosmetics.

Published in Journal of Functional Foods

ISSN: 1756-4646 (Print); 2214-9414 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply
Website: https://www.journals.elsevier.com/journal-of-functional-foods

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