Exploring the Phytochemical Profiles, and Antioxidant and Antimicrobial Activities of the Hydroethanolic Grape Pomace Extracts from Two Romanian Indigenous Varieties
Alexandru Cristian Grosu,
Filofteia Camelia Diguță,
Mircea-Cosmin Pristavu,
Aglaia Popa,
Florentina Badea,
Mihaela Dragoi Cudalbeanu,
Alina Orțan,
Ioan Dopcea,
Narcisa Băbeanu
Affiliations
Alexandru Cristian Grosu
Faculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania
Filofteia Camelia Diguță
Faculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania
Mircea-Cosmin Pristavu
Faculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania
Aglaia Popa
Faculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania
Florentina Badea
Faculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania
Mihaela Dragoi Cudalbeanu
Faculty of Land Reclamation and Environmental Engineering, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Mărăsti Blvd., 011464 Bucharest, Romania
Alina Orțan
Faculty of Land Reclamation and Environmental Engineering, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Mărăsti Blvd., 011464 Bucharest, Romania
Ioan Dopcea
CEBIS International, 47 Bd. Theodor Pallady, 032275 Bucharest, Romania
Narcisa Băbeanu
Faculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania
In this study, the potential value of dried grape pomace (whole, seed, and skin) obtained from Fetească Neagră (FN) and Tămâioasă Românească (TR) as a source of secondary metabolites was evaluated following hydroethanolic extraction. The total polyphenol, flavonoid, and anthocyanin contents of FN and TR extracts have been determined, along with their antioxidant and antimicrobial activities. The investigation of seeds and the whole pomace FN extracts revealed higher levels of polyphenol, flavonoid, and anthocyanin content in comparison to those extracted from TR. Fifteen polyphenolic compounds were identified through ultra-high-performance liquid chromatography (UHPLC) analysis. The most abundant concentrations of catechin and epicatechin were detected in seed and whole pomace extracts derived from both Romanian grape varieties. The antioxidant activity was higher in the whole pomace and skin extracts derived from FN than those derived from TR. The antimicrobial evaluation demonstrated that 15 out of 18 reference pathogenic bacteria exhibited low MIC and MBC values, indicating a strong antibacterial activity of FN and TR extracts. No anti-Candida activity was observed. It can be reasonably deduced that the Fetească Neagră and Tămâioasă Românească by-products represent a sustainable resource for the development of new functional ingredients for the pharmaceutical and food industries, in alignment with the principles of the circular bioeconomy.
