Ultrasound-Guided Radiofrequency Ablation: A New Attempt to the Treatment of Refractory Hyperparathyroidism Secondary to Chronic Kidney Disease

Dan-Ling Zhang; Sheng Chen; Mei-Zhu Gao; Yu-Cheng Lin; Fu-Yuan Hong; Zhen-Hui You; Xing Chen; Song-Song Wu

Kidney International Reports (Feb 2022)

Ultrasound-Guided Radiofrequency Ablation: A New Attempt to the Treatment of Refractory Hyperparathyroidism Secondary to Chronic Kidney Disease

Dan-Ling Zhang,
Sheng Chen,
Mei-Zhu Gao,
Yu-Cheng Lin,
Fu-Yuan Hong,
Zhen-Hui You,
Xing Chen,
Song-Song Wu

Affiliations

Dan-Ling Zhang: Department of Ultrasonography, Shengli Clinical College of Fujian Medical University, Fuzhou No. 7 Hospital, Fuzhou, People’s Republic of China
Sheng Chen: Department of Ultrasonography, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of China
Mei-Zhu Gao: Department of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of China
Yu-Cheng Lin: Department of Ultrasonography, Shengli Clinical College of Fujian Medical University, Affiliated Fuzhou First Hospital of Fujian Medical, Fuzhou, People’s Republic of China
Fu-Yuan Hong: Department of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of China
Zhen-Hui You: Department of General Surgery, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of China
Xing Chen: Department of General Surgery, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of China
Song-Song Wu: Department of Ultrasonography, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of China; Correspondence: Song-Song-Wu, Department of Ultrasonography, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, 134 East Street, Gu Lou District, Fuzhou City, Fujian Province, People’s Republic of China.

Journal volume & issue: Vol. 7, no. 2
pp. 282 – 288

Abstract

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Introduction: To evaluate clinical application value of radiofrequency ablation (RFA) in refractory hyperparathyroidism secondary to chronic kidney disease (CKD) by comparing the safety and effectiveness of RFA with parathyroidectomy with autotransplantation (PTX + AT). Methods: A retrospective study was conducted on 80 patients with CKD with refractory hyperparathyroidism who underwent RFA or PTX + AT between January 2018 and February 2021. Serum parathyroid hormone (PTH), calcium, and phosphorus levels, complications, clinical symptoms, visual analogue scale (VAS) scores, hospital stay duration, and postoperative recurrence rate were compared between the 2 groups. Results: Serum PTH, phosphorous, and calcium levels and the VAS scores improved significantly after RFA and PTX + AT (P 0.05), RFA markedly decreased the risk of severe hypocalcemia (SH) (20% vs. 46.67%; P 0.05). Conclusion: RFA can treat refractory secondary hyperparathyroidism (SHPT) with similar clinical efficacy as surgery and achieve faster recovery and a lower incidence of postoperative SH.

Published in Kidney International Reports

ISSN: 2468-0249 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology
Website: http://www.journals.elsevier.com/kidney-international-reports/

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