Kidney International Reports (Apr 2025)
Genetic Terminal Complement Deficiency in Israeli Bedouins With Kidney Failure
- Guy Chowers,
- Dror Ben-Ruby,
- Danit Atias-Varon,
- Omer Shlomovitz,
- Keren Slabodnik-Kaner,
- Maayan Kagan,
- Shany Avayou,
- Elvira Romanjuk,
- Boris Rogachev,
- Yosef S. Haviv,
- Ohad S. Birk,
- Noam Hadar,
- Younes Bathish,
- Iris Barshack,
- Alexander Volkov,
- Camila Avivi,
- Anna Pavlovsky,
- Orly Haskin,
- Amos J. Simon,
- Efrat Glick-Saar,
- Alina Ostrovsky,
- Mawada Assi,
- Ruth Schreiber,
- Dana Levin,
- Yoram Yagil,
- Mohammad Awawdeh,
- Karl Skorecki,
- Dan Dominissini,
- Alla Shnaider,
- Asaf Vivante
Affiliations
- Guy Chowers
- Department of Pediatrics B, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Dror Ben-Ruby
- Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Danit Atias-Varon
- Department of Pediatrics B, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Omer Shlomovitz
- Department of Pediatrics B, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Keren Slabodnik-Kaner
- Department of Pediatrics B, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Maayan Kagan
- Department of Pediatrics B, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Shany Avayou
- Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Elvira Romanjuk
- Department of Nephrology, Soroka University Medical Centre, Beer-Sheva, Israel; Faculty of Health Sciences, Ben Gurion University, Beer-Sheva, Israel
- Boris Rogachev
- Department of Nephrology, Soroka University Medical Centre, Beer-Sheva, Israel; Faculty of Health Sciences, Ben Gurion University, Beer-Sheva, Israel
- Yosef S. Haviv
- Department of Nephrology, Soroka University Medical Centre, Beer-Sheva, Israel; Faculty of Health Sciences, Ben Gurion University, Beer-Sheva, Israel
- Ohad S. Birk
- Faculty of Health Sciences, Ben Gurion University, Beer-Sheva, Israel; Genetics Institute at Soroka Medical Center, Beer-Sheva, Israel
- Noam Hadar
- Faculty of Health Sciences, Ben Gurion University, Beer-Sheva, Israel
- Younes Bathish
- Ziv Medical Center, Safed, Israel; The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
- Iris Barshack
- Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Institute of Pathology, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Alexander Volkov
- Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Institute of Pathology, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Camila Avivi
- Institute of Pathology, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Anna Pavlovsky
- Institute of Pathology, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Orly Haskin
- Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Institute of Nephrology, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
- Amos J. Simon
- Hemato-Immunology Unit, Hematology Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Sheba Cancer Research Centre, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Efrat Glick-Saar
- Sheba Cancer Research Centre, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Wohl Center for Translational Medicine, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Alina Ostrovsky
- Hemato-Immunology Unit, Hematology Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Mawada Assi
- Hemato-Immunology Unit, Hematology Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Ruth Schreiber
- Faculty of Health Sciences, Ben Gurion University, Beer-Sheva, Israel; Pediatric Nephrology Clinic, Soroka University Medical Center, Beer-Sheva, Israel
- Dana Levin
- Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Yoram Yagil
- Faculty of Health Sciences, Ben Gurion University, Beer-Sheva, Israel; A.P.C Health, Ramat-Gan, Israel; Department of Nephrology and Hypertension, Barzilai University Medical Center, Ashkelon, Israel
- Mohammad Awawdeh
- The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel; Hemodialysis Unit, Department of Internal Medicine, Holy Family Hospital, Nazareth, Israel
- Karl Skorecki
- The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel; Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa, Israel; Rambam Health Care Campus, Haifa, Israel
- Dan Dominissini
- Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Hemato-Immunology Unit, Hematology Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Sheba Cancer Research Centre, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Wohl Center for Translational Medicine, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
- Alla Shnaider
- Department of Nephrology, Soroka University Medical Centre, Beer-Sheva, Israel; Faculty of Health Sciences, Ben Gurion University, Beer-Sheva, Israel
- Asaf Vivante
- Department of Pediatrics B, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Genetic Kidney Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Pediatric Nephrology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Correspondence: Asaf Vivante, Department of Pediatrics B and Genetic Kidney Disease Research Laboratory, Edmond and Lily Safra Children’s Hospital and Sheba Medical Center, Tel Hashomer, Ramat Gan 5265601, Israel.
- DOI
- https://doi.org/10.1016/j.ekir.2025.01.019
- Journal volume & issue
-
Vol. 10,
no. 4
pp. 1274 – 1278
Abstract
No abstracts available.Keywords
- chronic kidney diseases
- complement
- ethnic minorities
- exome sequencing
- kidney failure
- terminal complement complex