Nature Communications (Sep 2021)
Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
- Romain Marlin,
- Veronique Godot,
- Sylvain Cardinaud,
- Mathilde Galhaut,
- Severin Coleon,
- Sandra Zurawski,
- Nathalie Dereuddre-Bosquet,
- Mariangela Cavarelli,
- Anne-Sophie Gallouët,
- Pauline Maisonnasse,
- Léa Dupaty,
- Craig Fenwick,
- Thibaut Naninck,
- Julien Lemaitre,
- Mario Gomez-Pacheco,
- Nidhal Kahlaoui,
- Vanessa Contreras,
- Francis Relouzat,
- Raphaël Ho Tsong Fang,
- Zhiqing Wang,
- Jerome Ellis,
- Catherine Chapon,
- Mireille Centlivre,
- Aurelie Wiedemann,
- Christine Lacabaratz,
- Mathieu Surenaud,
- Inga Szurgot,
- Peter Liljeström,
- Delphine Planas,
- Timothée Bruel,
- Olivier Schwartz,
- Sylvie van der Werf,
- Giuseppe Pantaleo,
- Mélanie Prague,
- Rodolphe Thiébaut,
- Gerard Zurawski,
- Yves Lévy,
- Roger Le Grand
Affiliations
- Romain Marlin
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Veronique Godot
- Vaccine Research Institute
- Sylvain Cardinaud
- Vaccine Research Institute
- Mathilde Galhaut
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Severin Coleon
- Vaccine Research Institute
- Sandra Zurawski
- Vaccine Research Institute
- Nathalie Dereuddre-Bosquet
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Mariangela Cavarelli
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Anne-Sophie Gallouët
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Pauline Maisonnasse
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Léa Dupaty
- Vaccine Research Institute
- Craig Fenwick
- Service of Immunology and Allergy Lausanne University Hospital
- Thibaut Naninck
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Julien Lemaitre
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Mario Gomez-Pacheco
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Nidhal Kahlaoui
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Vanessa Contreras
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Francis Relouzat
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Raphaël Ho Tsong Fang
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Zhiqing Wang
- Vaccine Research Institute
- Jerome Ellis
- Vaccine Research Institute
- Catherine Chapon
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- Mireille Centlivre
- Vaccine Research Institute
- Aurelie Wiedemann
- Vaccine Research Institute
- Christine Lacabaratz
- Vaccine Research Institute
- Mathieu Surenaud
- Vaccine Research Institute
- Inga Szurgot
- Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Peter Liljeström
- Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Delphine Planas
- Vaccine Research Institute
- Timothée Bruel
- Vaccine Research Institute
- Olivier Schwartz
- Vaccine Research Institute
- Sylvie van der Werf
- Molecular Genetics of RNA Viruses, Department of Virology, Institut Pasteur, CNRS UMR 3569, Université de Paris
- Giuseppe Pantaleo
- Vaccine Research Institute
- Mélanie Prague
- Vaccine Research Institute
- Rodolphe Thiébaut
- Vaccine Research Institute
- Gerard Zurawski
- Vaccine Research Institute
- Yves Lévy
- Vaccine Research Institute
- Roger Le Grand
- Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Université Paris-Saclay, Inserm, CEA
- DOI
- https://doi.org/10.1038/s41467-021-25382-0
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 9
Abstract
In this study, Marlin et al. provide insights into the potential use of subunit vaccines that induce a high level of protection against SARS-CoV-2 in animal models.
