Effects of flavonoids-rich Chinese bayberry (Myrica rubra Sieb. et Zucc.) pulp extracts on glucose consumption in human HepG2 cells

Xianan Zhang; Huizhong Huang; Xiaoyong Zhao; Qiang Lv; Chongde Sun; Xian Li; Kunsong Chen

Journal of Functional Foods (Apr 2015)

Effects of flavonoids-rich Chinese bayberry (Myrica rubra Sieb. et Zucc.) pulp extracts on glucose consumption in human HepG2 cells

Xianan Zhang,
Huizhong Huang,
Xiaoyong Zhao,
Qiang Lv,
Chongde Sun,
Xian Li,
Kunsong Chen

Affiliations

Xianan Zhang: Laboratory of Fruit Quality Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Zhejiang University, Zijingang Campus, Hangzhou 310058, China
Huizhong Huang: Laboratory of Fruit Quality Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Zhejiang University, Zijingang Campus, Hangzhou 310058, China
Xiaoyong Zhao: Laboratory of Fruit Quality Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Zhejiang University, Zijingang Campus, Hangzhou 310058, China
Qiang Lv: Laboratory of Fruit Quality Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Zhejiang University, Zijingang Campus, Hangzhou 310058, China
Chongde Sun: Laboratory of Fruit Quality Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; Zhejiang Key Laboratory for Agro-Food Processing, Development and Quality Improvement, Zhejiang University, Zijingang Campus, Hangzhou 310058, China
Xian Li: Laboratory of Fruit Quality Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; Zhejiang Key Laboratory for Agro-Food Processing, Development and Quality Improvement, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; Corresponding author. Laboratory of Fruit Quality Biology, Zhejiang University, Zijingang Campus, Hangzhou, 310058, China. Tel.:+86 571 88982630; fax: +86 571 88982224.
Kunsong Chen: Laboratory of Fruit Quality Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; Zhejiang Key Laboratory for Agro-Food Processing, Development and Quality Improvement, Zhejiang University, Zijingang Campus, Hangzhou 310058, China

Journal volume & issue: Vol. 14
pp. 144 – 153

Abstract

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Flavonoids composition of Chinese bayberry (Myrica rubra Sieb. et Zucc.) pulp extracts was characterized by LC-ESI-Q-TOF-MS and quantification of flavonoids in nine bayberry cultivars was carried out by HPLC. As a result, five flavonoids, i.e. cyanidin-3-O-glucoside (C-3-Glu), myricetin-3-O-rhamnoside (M-3-Rha), quercetin-3-O-galactoside (Q-3-Gal), quercetin-3-O-glucoside (Q-3-Glu), and quercetin-3-O-rhamnoside (Q-3-Rha) were identified and quantified. The glucose consumption activities of nine bayberry cultivars varied significantly among cultivars and they were well correlated with their total phenolics, total flavonoids contents, and DPPH scavenging activities. In addition, C-3-Glu and three quercetin-3-O-glycosides (Q-3-Glys, i.e. Q-3-Gal, Q-3-Glu, and Q-3-Rha), but not M-3-Rha, showed significant enhancement of glucose consumption in HepG2 cells. There were significant correlations between the glucose consumption activity with the contents of C-3-Glu and the sum of three Q-3-Glys, respectively. These results showed that bayberry cultivars with high content of C-3-Glu and Q-3-Glys may have great potential as hypoglycemic foods.

Published in Journal of Functional Foods

ISSN: 1756-4646 (Print); 2214-9414 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply
Website: https://www.journals.elsevier.com/journal-of-functional-foods

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