POS-378 SELECTIVE ETA ANTAGONIST ATRASENTAN, RAPIDLY REDUCES ALBUMINURIA AND DOWNREGULATES INTRA-RENAL PRO-INFLAMMATORY AND PRO-FIBROTIC TRANSCRIPTIONAL NETWORKS IN THE GDDY MOUSE MODEL OF SPONTANEOUS IGA NEPHROPATHY
A. KING,
R. Oballa,
M. Gunawan,
J. Cox,
J. Wu,
O. Chong,
J. Surendradoss,
J. Lester,
C. Nieh,
T. Kano,
Y. Suzuki
Affiliations
A. KING
Chinook Therapeutics, Research, Vancouver, Canada
R. Oballa
Chinook Therapeutics, Research, Vancouver, Canada
M. Gunawan
Chinook Therapeutics, Research, Vancouver, Canada
J. Cox
Chinook Therapeutics, Research, Vancouver, Canada
J. Wu
Chinook Therapeutics, Research, Vancouver, Canada
O. Chong
Chinook Therapeutics, Research, Vancouver, Canada
J. Surendradoss
Chinook Therapeutics, Research, Vancouver, Canada
J. Lester
Chinook Therapeutics, Research, Vancouver, Canada
C. Nieh
Chinook Therapeutics, Research, Vancouver, Canada
T. Kano
Juntendo University Faculty of Medicine, Nephrology, Tokyo, Japan
Y. Suzuki
Juntendo University Faculty of Medicine, Nephrology, Tokyo, Japan