The variation of the activity of Xenobiotic metabolizing enzymes with latitude as a potential factor in determining the course of history

Abstract

In this paper, we have presented evidence that correlates the latitudinal gradient in xenobiotic metabolizing enzymes to the (latitudinal) propensity for aggression and predatory acquisition of property and goods. A quantitative surrogate that confirms to this hypothesis is the pre-common-era direct correlation of the size of empire with latitude. The paper demonstrates a non-discountable influence of the selective pressure of (alkaloidal) food ingredients on geo-political and anthropological trajectories.