Iatreia (Apr 2016)

Cardiac resyncronization therapy with or without cardioverter-defibrillator versus defibrillator therapy alone, Pereira (Colombia): a cohort study

  • Arango- Franco, Ricardo,
  • Cárdenas-Castellanos, Juan Mauricio,
  • Rivera- Toquica, Álex Arnulfo,
  • Martínez, José William,
  • Marín-Medina, Daniel Stiven,
  • Orozco-Hernández,Juan Pablo,
  • Sosa-Urrea, Juan David,
  • Martínez- Muñoz, Manuel Andrés,
  • Sánchez-Duque, Jorge Andrés,
  • Granada-Muñoz, Viviana Andrea

Journal volume & issue
Vol. 29, no. 2
pp. 133 – 143


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Objective: To evaluate survival in patients with cardiac resynchronization with or without cardioverterdefibrillator versus patients with implantable cardioverter-defibrillator alone Materials and methods: Retrospective cohort, the primary end point was death from cardiac causes, the exposure was electrophysiological therapies, and the information sources were medical files and other records. Results: 70 elderly patients with functional devices; 82 % of them received optimized medical therapy. No significant association was found between survival of patients with cardiac resynchronization therapy with or without defibrillator and cardioverter-defibrillator therapy alone (log rank test, p = 0.54), but the former had a longer survival time (ANOVA p = 0.0012). The hazard ratio was 0.017 for day 371 and 0.15 for day 2169. Fourteen deaths occurred during the observation period, three of them from non-cardiac causes. Conclusion: Cardiac resynchronization therapy was associated with significantly longer survival time.