Phytochemical composition and antioxidant, anti-inflammatory and antimicrobial activities of Juniperus macrocarpa Sibth. et Sm.

Marija M. Lesjak; Ivana N. Beara; Dejan Z. Orčić; Knežević N. Petar; Nataša Đ. Simin; Svirčev Đ. Emilija; Neda M. Mimica-Dukić

Journal of Functional Foods (Mar 2014)

Phytochemical composition and antioxidant, anti-inflammatory and antimicrobial activities of Juniperus macrocarpa Sibth. et Sm.

Marija M. Lesjak,
Ivana N. Beara,
Dejan Z. Orčić,
Knežević N. Petar,
Nataša Đ. Simin,
Svirčev Đ. Emilija,
Neda M. Mimica-Dukić

Affiliations

Marija M. Lesjak: Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia; Corresponding author. Tel.: +381 21 4852755; fax: +381 21 454065.
Ivana N. Beara: Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia
Dejan Z. Orčić: Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia
Knežević N. Petar: Department of Biology and Ecology, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 2, 21000 Novi Sad, Serbia
Nataša Đ. Simin: Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia
Svirčev Đ. Emilija: Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia
Neda M. Mimica-Dukić: Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia

Journal volume & issue: Vol. 7
pp. 257 – 268

Abstract

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The phenolic and terpene profiles, as well as antioxidant, anti-inflammatory and antimicrobial activities of extracts and essential oils of Juniperus macrocarpa species were studied. The content of 45 phenolics was determined using LC–MS/MS. Accordingly, significantly different compositions were found between leaves and seed cones extracts, while the dominant compounds were rutin, catechin, quercitrin, epicatechin and amentoflavone. GC–MS showed simple terpene composition, with monoterpenes being dominant and α-pinene as the most abundant compound. Extracts and essential oils of J. macrocarpa showed moderate antioxidant activity comparable to that of butylated hydroxyanisole (BHA). Seed cones showed significant anti-inflammatory activity, with high pro-inflammatory activity of extract towards production of PGE2. Essential oils demonstrated considerable antimicrobial activity against Gram positive bacteria, especially leaves against Clostridium perfringens. J. macrocarpa showed noteworthy biopotential and its usage in food and beverage manufacturing and as a source of potent herbal drugs should be considered.

Published in Journal of Functional Foods

ISSN: 1756-4646 (Print); 2214-9414 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply
Website: https://www.journals.elsevier.com/journal-of-functional-foods

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