npj Vaccines (Oct 2024)

Regulatory review of benefits and risks of preventing infant RSV disease through maternal immunization

  • Yugenia K. Hong-Nguyen,
  • Joseph Toerner,
  • Lucia Lee,
  • Maria C. Allende,
  • David C. Kaslow

DOI
https://doi.org/10.1038/s41541-024-01002-y
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 3

Abstract

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Abstract In August 2023, FDA approved Abrysvo for active immunization of pregnant individuals at 32 through 36 weeks gestational age to prevent lower respiratory tract disease (LRTD), including severe LRTD, caused by respiratory syncytial virus (RSV) in infants from birth through 6 months of age. A pragmatic approach to narrow the interval of use of Abrysvo in pregnant individuals balanced benefits of vaccine effectiveness against potential risks to infant and mother.