Have existing pharmaceutical excipients failed to enable oral/nasal protein delivery?

Abstract

It seems evident that the ill-defined weltanschauung of the past decade of enabling oral un-truncated permeability-dependent protein delivery carte-blanche using existing excipients has produced sparse results. Existing excipients are better utilized at exploiting niches which do not require either permeation or permeation enhancement incongruent and/or disproportionate to the existing excipient molecules’ ability.