New heterocycles having double characters; as antimicrobial and surface active agents.

Abstract

Fatty acids isothiocyanate (1) was used as a starting material to synthesize some important heterocycles such as triazoles, oxazoles, thiazoles, benzoxazoles and quinazolines by treating with different types of nucleophiles such as nitrogen nucleophiles, oxygen nucleophiles, and sulfur nucleophiles. The produced compounds were subjected to propylene oxide in different moles (n = 3, 5 and 7) to produce novel groups of nonionic compounds having the double function as antimicrobial and surface active agents which can be used in the manufacturing of drugs, cosmetics, pesticides or can be used as antibacterial and/or antifungal. The physical properties as surface and interfacial tension, cloud point, foaming height, wetting time, emulsification power and the critical micelle concentration (CMC) were determined, antimicrobial and biodegradability were also determined.

Keywords

• antimicrobial
• fatty acid isothiocyanate
• heterocycles
• surface active agents