Bi-allelic REN Mutations and Undetectable Plasma Renin Activity in a Patient With Progressive CKD

• Sofia Jorge,
• Kendrah Kidd,
• Petr Vylet’al,
• Estela Nogueira,
• Lauren Martin,
• Katrice Howard,
• Veronika Barešová,
• Kateřina Hodaňová,
• Aleš Hnízda,
• Oana Moldovan,
• Catarina Silveira,
• Ana Margarida Coutinho,
• José António Lopes,
• Anthony J. Bleyer,
• Stanislav Kmoch,
• Martina Živná

Affiliations

Sofia Jorge

Department of Nephrology and Renal Transplant, Hospital de Santa Maria, CHULN, EPE, Lisbon, Portugal

Kendrah Kidd

Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic; Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

Petr Vylet’al

Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

Estela Nogueira

Department of Nephrology and Renal Transplant, Hospital de Santa Maria, CHULN, EPE, Lisbon, Portugal

Lauren Martin

Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

Katrice Howard

Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

Veronika Barešová

Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

Kateřina Hodaňová

Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

Aleš Hnízda

Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

Oana Moldovan

Genetic Department of Hospital de Santa Maria, CHULN, EPE, Lisbon, Portugal

Catarina Silveira

GenoMed - Diagnósticos de Medicina Molecular, S.A., Lisbon, Portugal

Ana Margarida Coutinho

GenoMed - Diagnósticos de Medicina Molecular, S.A., Lisbon, Portugal

José António Lopes

Department of Nephrology and Renal Transplant, Hospital de Santa Maria, CHULN, EPE, Lisbon, Portugal

Anthony J. Bleyer

Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic; Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

Stanislav Kmoch

Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic; Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

Martina Živná

Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic; Correspondence: Martina Živná, Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Ke Karlovu 2, Prague 2, 120 00, Czech Republic.