Turkish Journal of Agriculture: Food Science and Technology (Dec 2016)

Epigenetics Regulators of Genomic Imprinting in Mammals

  • Zeynep Demirtaş,
  • Fatih Bilgi,
  • Levent Mercan

DOI
https://doi.org/10.24925/turjaf.v4i12.1139-1142.958
Journal volume & issue
Vol. 4, no. 12
pp. 1139 – 1142

Abstract

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Genomic imprinting is expression of gene’s only one allele in one of homolog chromosome depending on its maternal or paternal origin. A waste number of genes which are under the imprinting effect were identified as it has a key role in mammalian growth. The first three genes which is identified as imprinted are Igf2r, Igf2 and H19 which are first discovered in mouse genome. Over a hundred genes are identified as imprinted in mammals. Most of the imprinted genes are considered as they have a key role in growth and differentiation. In this review, epigenetic regulators of imprinted genes in mammals were mentioned.

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