Effects of Protein Nutrition Mode under Guangxi Longevity Dietary Pattern on D-Galactose Induced Aging Mice

Abstract

This research adopted the D-galactose induced senility mice as the research object, under the condition of constant energy control, different protein content of feeding groups was designed. Mice were under dietary intervention for 8 weeks, by analyzing the Morris water maze data, brain tissue slice and liver tissue antioxidant capacity to explore the anti-aging effect of protein nutrition in Guangxi longevity dietary patterns. The results showed that: Compared with the high (P/C=1/2), medium (P/C=1/3) and low (P/C=1/5) protein diet groups, the escape latency of mice in P/C=1/4 (protein/carbohydrate) group significantly decreased (P P/C=1/5 group > P/C=1/3 group > young control group > P/C=1/2 group > aging control group. In summary, mice in P/C=1/4 low-protein diet group can effectively resist the senior-induced injury of D-galactose, and maintain strong learning and memory ability and antioxidant ability, thus showing strong anti-aging effect. The results of this study would provide a theoretical basis for the relationship between dietary protein nutrition and health as well as longevity.

Keywords

• longevity dietary pattern
• protein nutrition mode
• d-gal induced senility mice
• oxidative stress
• learning and memory ability