Journal of Acute Disease (Jan 2017)

Noninvasive ventilation in cancer children with acute respiratory failure

  • Sema Yilmaz,
  • Riza Dincer Yildizdas,
  • Oguz Dursun,
  • Bulent Karapinar,
  • Tanil Kendirli,
  • Demet Demirkol,
  • Agop Citak,
  • Alphan Kupesiz,
  • Hakan Tekguc,
  • Muhterem Duyu,
  • Pinar Yazici,
  • Ufuk Yukselmis,
  • Caglar Odek,
  • Ayhan Yaman,
  • Suleyman Bayraktar,
  • Guntulu Şık,
  • Fatma Betul Cakir

DOI
https://doi.org/10.12980/jad.6.2017JOAD_2016_46
Journal volume & issue
Vol. 6, no. 1
pp. 23 – 27

Abstract

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Objective: To establish the effectiveness of noninvasive ventilation in cancer children with acute respiratory failure. Methods: The data of 33 cancer patients were obtained prospectively from six different pediatric intensive care units in Turkey between the years of 2012 and 2013. >Results: The diagnosis was leukemias in 25 (75.8%), lymphomas in 3 (9.1%) and other solid tumors in 5 (15.1%) patients. Pneumonia in 12 (36.3%) and sepsis in 15 (45.4%) patients were seen as the common reasons of respiratory failure. The mean PaO2/FiO2 ratios were (164.22 ± 37.24) and (126.80 ± 42.73) in noninvasive ventilation success and failure group, respectively. Noninvasive ventilation was successful in 18 (54.5%) patients. The failure group consisted of 15 patients required intubation. A total of 14 (42.4%) patients died. The clinical outcome in terms of success and failure was meaningful statistically (P = 0.0 00 1). >Conclusions: Our results could encourage the use of noninvasive ventilation in children with cancer who develop acute respiratory failure. It should be considered as a useful therapeutic approach to avoid endotracheal intubation

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