A NEW AND CONCISE SYNTHESIS OF 3-HYDROXYLATED 3-ARYLISOINDOLINONES NOUVELLE TECHNIQUE D'ASSEMBLAGE DE 3-ARYLISOINDOLINONES HYDROXYLEES EN POSITION 3

Abstract

A new technique for the assembly of diversely substituted 3-hydroxy(alkoxy)-3-arylisoindolinones has been developed. This new synthetic route is based upon the anionic cyclization of suitably substituted halogenoaroyl acylamines as the key step and gives access to a variety of highly functionalized models.

Keywords

• diacylamines
• metal-halogen conversion
• anionic cyclization
• Parham type cyclization
• isoindolinones