A review on anti-cancer effect of green tea catechins

Zhe Cheng; Zhifa Zhang; Yu Han; Jing Wang; Yongyong Wang; Xiaoqiang Chen; Yundong Shao; Yong Cheng; Weilong Zhou; Xiaolei Lu; Zhengqi Wu

Journal of Functional Foods (Nov 2020)

A review on anti-cancer effect of green tea catechins

Zhe Cheng,
Zhifa Zhang,
Yu Han,
Jing Wang,
Yongyong Wang,
Xiaoqiang Chen,
Yundong Shao,
Yong Cheng,
Weilong Zhou,
Xiaolei Lu,
Zhengqi Wu

Affiliations

Zhe Cheng: National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, Wuhan 430068, China; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing 100048, China
Zhifa Zhang: Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Yu Han: National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, Wuhan 430068, China; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing 100048, China
Jing Wang: School of Food and Health, Beijing Technology and Business University (BTBU), Beijing 100048, China
Yongyong Wang: Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Xiaoqiang Chen: National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, Wuhan 430068, China; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing 100048, China; Corresponding author at: National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, Wuhan 430068, China.
Yundong Shao: Zhejiang Skyherb Biotechnology Inc., Anji 313300, China
Yong Cheng: Zhejiang Skyherb Biotechnology Inc., Anji 313300, China
Weilong Zhou: China National Center of Quality Supervision and Inspection of Tea, Hangzhou Tea Research Institute, China COOP, Hangzhou 310016, China
Xiaolei Lu: China National Center of Quality Supervision and Inspection of Tea, Hangzhou Tea Research Institute, China COOP, Hangzhou 310016, China
Zhengqi Wu: National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, Wuhan 430068, China

Journal volume & issue: Vol. 74
p. 104172

Abstract

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This article reviewed inhibitory activities of green tea catechins (GTCs) against various tumorigenesis and their suppressive effects on cancer cell progression, metastasis, and angiogenesis according to a great number of kinds of literature, and then summarized the mechanisms of tea catechins-mediated cancer prevention in various cancer types. Special emphasis was placed on summarizing recent research highlighting the related techniques in improving GTCs’ effectiveness in the prevention of tumor progression and/or treatment of cancers. Synergistic effects of catechins when combined with other phytochemicals and drugs, nanostructure- based delivery system, and molecular modifications of EGCG and catechins as means were discussed, and thus provide the basis to better utilize GTCs as the main ingredient of functional foods to reduce the risk of human cancer.

Published in Journal of Functional Foods

ISSN: 1756-4646 (Print); 2214-9414 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply
Website: https://www.journals.elsevier.com/journal-of-functional-foods

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