Global Biosecurity (May 2020)
COVID-19: the gut to lung hypothesis
Abstract
Increasingly COVID-19 is being recognised as a multisystem disease, with viral replication within the gastrointestinal tract now being well accepted. This article collates evidence pointing to possible gastrointestinal transmission as well as outlining possible mechanisms for intra-institutional or cruise ship spread, and explores the possible impact of gastrointestinal replication on disease course.
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