Prevalence and Severity of Dermatological Condition-Associated Skin Pain in the Chinese

Abstract

Xiaohua Wang,1,* Qingsong Lai,2,* Baoqing Zheng,1 Li Ye,1 Si Wen,1 Yunling Yan,1 Bin Yang,1 Mao-Qiang Man1 1Dermatology Hospital, Southern Medical University, Guangdong 510095, People’s Republic of China; 2Puning City Chronic Disease Prevention and Control Center, Guangdong 515300, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mao-Qiang Man; Bin Yang Email [email protected]; [email protected]/Aim: Although the characteristics of cutaneous sensory symptoms in the general population have been documented, dermatological condition-associated skin pain has not been characterized yet. In the present study, we aimed to characterize dermatological condition-associated skin pain in the Chinese.Subjects and Methods: A questionnaire was given to outpatients to identify self-proclaimed skin pain at our dermatology clinic. The severity of skin pain was assessed using pain scale 0– 10. Prevalence and pain severity were compared between males and females.Results: A total of 2144 patients, including 1254 females and 890 males aged 13– 94 years, were included in this study. The overall prevalence of skin pain was 9.93% in this cohort. The prevalence of skin pain varied greatly with dermatological conditions (p< 0.0001). Moreover, a higher prevalence of skin pain was observed in males than in females (p< 0.05). Among the dermatological conditions reported, higher skin pain scales were found in subjects with either glucocorticoid-induced dermatitis (4.20 ± 0.73) or herpes zoster (4.00 ± 0.29). While the overall pain scales were comparable between males and females (2.38 ± 0.13 versus 2.68 ± 0.13), pain scales in patients with eczematous dermatitis were higher in females than in males (p< 0.05). Furthermore, pain scales correlated positively with age. However, pain scales did not differ between subjects with versus without a family history of cutaneous sensory symptoms. These results demonstrate that the prevalence and severity of dermatological condition-associated skin pain vary with dermatological conditions and gender in the Chinese.Conclusion: Patients with some dermatological conditions may experience skin pain. Although the pain is moderate, it can negatively impact the quality of patients’ lives. Alleviation of skin pain should be considered when treating patients with certain dermatological conditions.Keywords: skin disorders, skin pain, gender, prevalence

Keywords

• skin disorders
• skin pain
• gender
• prevalence