Journal of Vasyl Stefanyk Precarpathian National University (May 2015)
INVOLVEMENT OF CATALASE IN SACCHAROMYCES CEREVISIAE HORMETIC RESPONSE TO HYDROGEN PEROXIDE
Abstract
In this study, we investigated the relationship between catalase activity and H2O2-induced hormetic response in budding yeast S. cerevisiae. In general, our data suggest that: (i) hydrogen peroxide induces hormesis in a concentration- and time-dependent manner; and (ii) the effect of hydrogen peroxide on yeast colony growth positively correlates with the activity of catalase that suggests the enzyme involvement in overall H2O2-induced stress response and hormetic response in yeast.